What Is a GLP-1? A Complete Guide to Semaglutide & Tirzepatide

Learn what GLP-1 medications like semaglutide and tirzepatide are, how they work for weight loss and hormone balance, and why they’re transforming women’s health.

Wellness NP

10/12/20252 min read

women doing exercise raising left hands while holding dumbbells inside room
women doing exercise raising left hands while holding dumbbells inside room

What Is a GLP-1?

A Complete Guide to Semaglutide and Tirzepatide

If you’ve been hearing the buzz around GLP-1 medications like semaglutide (Ozempic®, Wegovy®) or tirzepatide (Mounjaro®, Zepbound®), you’re not alone. These medications have completely changed how we approach weight loss, blood sugar balance, and metabolic health. But what exactly are GLP-1s—and how do they work? Let’s break it down.

💡 What Does “GLP-1” Mean?

GLP-1 stands for glucagon-like peptide-1, a naturally occurring hormone your body makes in the gut after you eat. Its job? To help regulate blood sugar, appetite, and digestion.

Here’s what GLP-1 does naturally:

  • Signals fullness to your brain so you stop eating when satisfied

  • Slows digestion to keep you feeling full longer

  • Supports insulin release and lowers blood sugar

  • Reduces glucagon, a hormone that raises blood sugar

In other words, GLP-1 is your body’s built-in “metabolic messenger.”

💉 How GLP-1 Medications Work

Medications like semaglutide and tirzepatide are designed to mimic or enhance the natural GLP-1 hormone.

  • Semaglutide is a GLP-1 receptor agonist, meaning it activates the GLP-1 receptor to improve blood sugar control and reduce appetite.

  • Tirzepatide is a dual GIP/GLP-1 agonist—it targets two metabolic pathways (GIP and GLP-1), which may enhance both weight loss and insulin sensitivity.

These medications essentially help your body re-learn how to regulate hunger and metabolism the way it was designed to—before hormones, stress, and modern lifestyles got in the way.

⚖️ Benefits Beyond Weight Loss

While GLP-1s are most known for weight loss, the science goes deeper. Studies show they can:

  • Lower A1C and improve blood sugar control

  • Reduce inflammation and oxidative stress

  • Lower cardiovascular risk (protecting your heart)

  • Improve fatty liver and insulin resistance

  • Support hormone balance, especially in women with PCOS or perimenopause

If you're interested in getting started on a GLP1, click here to check eligibility. Use code MICHELLE to save $100.

🧬 Semaglutide vs. Tirzepatide: What’s the Difference?

|Feature Semaglutide Tirzepatide _______________________________________________________________________________________________________________________

Brand Names Ozempic®, Wegovy® Mounjaro®, Zepbound®

Mechanism GLP-1 receptor agonist Dual GIP + GLP-1 agonist

Injection Weekly Weekly

Average Weight Loss 10–15 % of body weight 15–22 % of body weight

Blood Sugar Control Excellent Superior in many studies

Common Side Effects Nausea, fullness, fatigue Similar, sometimes milder

Ideal For Those focused on blood-sugar& appetite regulation Those needing added insulin-sensitivity &

enhanced fat loss

🌿 Why GLP-1s Work So Well for Women

Women, especially in perimenopause or menopause, often struggle with stubborn belly fat, bloating, and blood sugar swings. GLP-1s help address the root causeinsulin resistance and hormonal imbalance—not just the number on the scale.

By improving metabolic flexibility, reducing inflammation, and restoring appetite control, these medications can help women feel more energized, balanced, and in control of their health again.

💬 The Bottom Line

GLP-1 medications like semaglutide and tirzepatide are more than just weight loss injections—they’re a reset for your metabolism and hormones. When combined with proper nutrition, hydration, movement, and lifestyle support, they can help you achieve lasting, sustainable wellness.

✨ Ready to Start Your GLP-1 Journey?

Before beginning any medication, talk with a qualified healthcare provider who understands women’s metabolism and hormone health. If you're interested in starting a compound GLP1 with a Telehealth company click here. Use code MICHELLE to save $100. As always, though I am a provider, I am not your provider and you should always consult with your own healthcare provider regarding your health and wether any supplement or medication is right for your unique situation.

👉 Download my free “GLP-1 Starter Checklist to learn how to start safely and get the best results on your journey.

(This article contains affiliate links, which means I may earn a commission at no additional cost to you.)